TNER: a novel background error suppression method for mutation detection in circulating tumor DNA
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چکیده
منابع مشابه
Circulating tumor DNA outperforms circulating tumor cells for KRAS mutation detection in thoracic malignancies.
BACKGROUND Circulating biomarkers, such as circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA), are both considered for blood-based mutation detection, but limited studies have compared them in a head-to-head manner. Using KRAS (Kirsten rat sarcoma viral oncogene homolog), we performed such a comparison in patients who underwent surgery for suspected lung cancer. METHODS We recru...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2018
ISSN: 1471-2105
DOI: 10.1186/s12859-018-2428-3